Po'boys · Uptown, New Orleans

Domilise's Po-Boy & Bar

Domilise's Po-Boy & Bar: Po'boys in Uptown, New Orleans. Critics: 83% liked it, from 5 reviews (2022 to 2025). Order: Fried shrimp po'boy, or half-and-half oyster and shrimp.

Michelin Bib Gourmand (2025)Where to eat fried shrimp po'boySandwich shop

What to order

Fried shrimp po'boy, or half-and-half oyster and shrimp

Why go

An Uptown sandwich shop open since 1918, known for hot-sauced fried shrimp po'boys.

Family-run Uptown sandwich counter, a po'boy purist's pick for generations and named in every roundup.

What the critics say

Critics: 83% liked it, from 5 reviews (2022 to 2025). Written up by Michelin Guide 2025, The Infatuation 2025, Time Out.

On Chef Amazing’s lists

Breakfast and sandwiches in New OrleansThe big-night tables of New Orleans
Neighborhood
Uptown
Price
$
Add to Chef Amazing Open in MapsSee it in the New Orleans guide

Seen in axios.com, timeout.com, New Orleans & Company

Also nearby in Uptown

Guy’s Po-BoysAcamayaAcme Oyster HouseBrennan'sBrigtsen'sCafé du MondeCentral GroceryChicken's Kitchen
Plan my New Orleans food tripWhere to eat in New Orleans

Researched October 23, 2026 from the sources linked above. Places change; confirm hours and reservations before you go.

Chef Amazing · Will Travel for Food · New Orleans · 250 food markets